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Whitehawk Therapeutics, Inc.

3.70

-0.0600-1.60%

Post-market: 3.700.00000.00%19:30 EDT

Volume:431.79K

Turnover:1.60M

Market Cap:210.93M

PE:-3.32

High:3.81

Open:3.81

Low:3.66

Close:3.76

52wk High:5.50

52wk Low:1.87

Shares:57.01M

Float Shares:28.74M

Volume Ratio:1.89

T/O Rate:1.50%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-1.1137

EPS(LYR):-0.3328

ROE:-44.98%

ROA:-28.70%

PB:1.15

PE(LYR):-11.12

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Overview Company News Filings

Whitehawk Therapeutics announces $87.5M private placement

BRIEF-Whitehawk Therapeutics Announces $87.5M Private Placement Equity Financing

Whitehawk Therapeutics prices USD 87.5 million PIPE at USD 3.92 per share

WhiteHawk Therapeutics Announces $87.5M Private Placement Equity Financing

THOMSON REUTERS

Natural gas mineral firm WhiteHawk reveals sevenfold revenue surge in US IPO filing

Oppenheimer Sticks to Its Buy Rating for Whitehawk Therapeutics (WHWK)

Analysts’ Opinions Are Mixed on These Healthcare Stocks: Whitehawk Therapeutics (WHWK), Prime Medicine, Inc. (PRME) and Argenx Se (ARGX)

Whitehawk Therapeutics Inc reports results for the quarter ended March 31 - Earnings Summary

Whitehawk Therapeutics posts corporate deck outlining three-asset antibody-drug conjugate pipeline

Whitehawk Q1 net loss turns to USD 22.2 million

WhiteHawk Therapeutics Reports First Quarter 2026 Financial Results and Recent Highlights

THOMSON REUTERS

Whitehawk Therapeutics Inc expected to post a loss of 9 cents a share - Earnings Preview

Whitehawk Therapeutics announces annual shareholder meeting

Whitehawk Therapeutics' Antibody Drug Conjugates Indicate Potential Efficacy Against Cancer, Oppenheimer Says

MT Newswires Live

Oppenheimer Sticks to Their Buy Rating for Whitehawk Therapeutics (WHWK)

Analysts’ Opinions Are Mixed on These Healthcare Stocks: Whitehawk Therapeutics (WHWK), COMPASS Pathways (CMPS) and Monopar Therapeutics Inc (MNPR)

Whitehawk Therapeutics publishes HWK-016 preclinical presentation on MUC16-targeting ADC

Whitehawk announces presentation of new preclinical data across ADC portfolio

Whitehawk says Phase 1 trial for HWK-016 ADC in ovarian, endometrial cancers ongoing

Whitehawk Therapeutics CEO joins Jones Trading Post-AACR virtual fireside chat

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announced an $87.5 million PIPE financing through an unregistered sale of common stock and pre-funded warrants.Deal includes 4,330,866 common shares priced at USD 3.92 per share.Also selling pre-funded warrants for 17,991,021 shares priced at USD 3.92 per warrant, with an exercise price of USD 0.0001 per share.Proceeds earmarked for working capital, general corporate purposes, ADC pipeline development; cash runway expected into second half of 2028.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260513:nNDL85lhgp:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["WHWK","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635810097","title":"WhiteHawk Therapeutics Announces $87.5M Private Placement Equity Financing","url":"https://stock-news.laohu8.com/highlight/detail?id=2635810097","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635810097?lang=en_us&edition=fundamental","pubTime":"2026-05-13 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18:28","pubTimestamp":1778495281,"startTime":"0","endTime":"0","summary":"UPDATE 3-Natural gas mineral firm WhiteHawk reveals sevenfold revenue surge in US IPO filingAdds analyst comment and background in paragraphs 6-9","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260511:nL4N41O0OF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4127","RJF","BK4588","BK4139","IE00B64PRP62.GBP","LU1804176565.USD","WHWK","IE00BGHQF748.EUR","LU2265009873.SGD","LU1363072403.SGD","SF","IE00B3QW5Z07.USD","BK4585","LU0971096721.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633879451","title":"Oppenheimer Sticks to Its Buy Rating for Whitehawk Therapeutics (WHWK)","url":"https://stock-news.laohu8.com/highlight/detail?id=2633879451","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633879451?lang=en_us&edition=fundamental","pubTime":"2026-05-08 21:00","pubTimestamp":1778245250,"startTime":"0","endTime":"0","summary":"Oppenheimer analyst Jeff Jones reiterated a Buy rating on Whitehawk Therapeutics today and set a price target of $7.00. According to TipRanks, Jone...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/oppenheimer-sticks-to-its-buy-rating-for-whitehawk-therapeutics-whwk-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/oppenheimer-sticks-to-its-buy-rating-for-whitehawk-therapeutics-whwk-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["WHWK","OPY"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633417313","title":"Analysts’ Opinions Are Mixed on These Healthcare Stocks: Whitehawk Therapeutics (WHWK), Prime Medicine, Inc. (PRME) and Argenx Se (ARGX)","url":"https://stock-news.laohu8.com/highlight/detail?id=2633417313","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633417313?lang=en_us&edition=fundamental","pubTime":"2026-05-08 03:10","pubTimestamp":1778181013,"startTime":"0","endTime":"0","summary":"Companies in the Healthcare sector have received a lot of coverage today as analysts weigh in on Whitehawk Therapeutics (WHWK), Prime Medicine, Inc...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-whitehawk-therapeutics-whwk-prime-medicine-inc-prme-and-argenx-se-argx-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-whitehawk-therapeutics-whwk-prime-medicine-inc-prme-and-argenx-se-argx-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IE0034235188.USD","IE00BJJMRZ35.SGD","LU0320765992.SGD","LABU","XLV","LU0109394709.USD","BK4137","LU0128526141.USD","XBI","IE00B4R5TH58.HKD","LU2324357040.USD","IE0009355771.USD","LU0029874061.USD","IE00BFTCPJ56.SGD","PRME","BK4505","BK4585","IE00B2B36J28.USD","LU1983260115.SGD","ARGX","IE0002141913.USD","BK4139","LU0889565916.HKD","WHWK","BK4588","BK4581","HCSG","IE00BJT1NW94.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633412903","title":"Whitehawk Therapeutics Inc reports results for the quarter ended March 31 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2633412903","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633412903?lang=en_us&edition=fundamental","pubTime":"2026-05-07 23:28","pubTimestamp":1778167717,"startTime":"0","endTime":"0","summary":"Whitehawk Therapeutics Inc reports results for the quarter ended March 31 - Earnings SummaryWhitehawk Therapeutics Inc WHWK.OQ reported a quarterly adjusted loss of 32 cents per share for the quarter ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nL8N41K2A3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","WHWK"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633144774","title":"Whitehawk Therapeutics posts corporate deck outlining three-asset antibody-drug conjugate pipeline","url":"https://stock-news.laohu8.com/highlight/detail?id=2633144774","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633144774?lang=en_us&edition=fundamental","pubTime":"2026-05-07 20:17","pubTimestamp":1778156233,"startTime":"0","endTime":"0","summary":"Whitehawk outlined a three-asset antibody-drug conjugate portfolio, including 2 clinical-stage programs and an IND expected mid-2026.Cash as of March 31, 2026 was USD 123 million, with runway expected into 2028 under current plans.Platform positioned around a DAR6 TOP1 inhibitor payload and cleavable linker, with preclinical benchmarks cited at 3-10x greater potency, 5-25x higher stability, and 2-3x higher safety margin versus an average TOP1 inhibitor ADC platform.Lead programs include HWK-007 targeting PTK7 and HWK-016 targeting MUC16, with first data readouts expected in 1H 2027.Third program HWK-206 targets SEZ6, with Phase 1 planned in small cell lung cancer and neuroendocrine neoplasms.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advi","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nNDLdv0b9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","WHWK"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633144325","title":"Whitehawk Q1 net loss turns to USD 22.2 million","url":"https://stock-news.laohu8.com/highlight/detail?id=2633144325","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633144325?lang=en_us&edition=fundamental","pubTime":"2026-05-07 20:04","pubTimestamp":1778155486,"startTime":"0","endTime":"0","summary":"Whitehawk Therapeutics posted a net loss of USD 22.2 million, swinging from net income of USD 73 million a year earlier.Research and development expenses climbed to USD 17.2 million from USD 8.8 million, including USD 5.3 million of development milestone expenses under a license agreement with WuXi Biologics.Cash, cash equivalents, short-term investments fell to USD 123 million at March 31 from USD 145.7 million at Dec. 31; cash runway seen funding operations into 2028.Phase 1 dose-escalation studies for HWK-007 and HWK-016 continued enrolling; IND submission for HWK-206 remains on track for mid-2026 with Phase 1 recruitment planned to start in Q3 2026.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nNDL6tttYH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0516422366.SGD","LU0823426308.USD","LU3063872942.SGD","BK1141","BK1610","LU0327786744.USD","LU0819121731.USD","LU0979878070.USD","02269","LU0417516738.SGD","IE00B0JY6N72.USD","SG9999002463.SGD","LU0516422952.EUR","LU0043850808.USD","LU0516423091.SGD","LU1242518857.USD","LU0588546209.SGD","LU0359201612.USD","LU1720050803.USD","BK1576","LU0359202008.SGD","LU0417516902.SGD","LU0856984785.SGD","LU0051755006.USD","LU0572944931.SGD","LU1880383366.USD","LU0456846285.SGD","LU0307460666.USD","LU1688375341.USD","LU0140636845.USD","WHWK","BK1521","BK4139","SG9999002562.SGD","BK1589","LU0052750758.USD","LU0181495838.USD","LU0039217434.USD","LU1794554557.SGD","LU0326950275.SGD","LU0823426480.USD","LU0456827905.SGD","LU0708995583.HKD","LU0348825331.USD","LU0516422440.USD","LU0348735423.USD","LU0516423174.USD","LU1242518931.SGD","LU0320764599.SGD","LU2039709279.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633412211","title":"WhiteHawk Therapeutics Reports First Quarter 2026 Financial Results and Recent Highlights","url":"https://stock-news.laohu8.com/highlight/detail?id=2633412211","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633412211?lang=en_us&edition=fundamental","pubTime":"2026-05-07 20:00","pubTimestamp":1778155206,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260507:nTUA8S4RTT:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["WHWK","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2633396241","title":"Whitehawk Therapeutics Inc  expected to post a loss of 9 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2633396241","media":"Reuters","labels":["dataReport","preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2633396241?lang=en_us&edition=fundamental","pubTime":"2026-05-05 07:03","pubTimestamp":1777935787,"startTime":"0","endTime":"0","summary":"Whitehawk Therapeutics Inc  expected to post a loss of9cents a share - Earnings Preview Whitehawk Therapeutics Inc WHWK.OQ WHWK.O is expected to  show a fall in quarterly revenue when it reports  resu","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260504:nL8N41H2O6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport,preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","WHWK"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631535022","title":"Whitehawk Therapeutics announces annual shareholder meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2631535022","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631535022?lang=en_us&edition=fundamental","pubTime":"2026-04-29 04:29","pubTimestamp":1777408188,"startTime":"0","endTime":"0","summary":"Whitehawk Therapeutics scheduled 2026 annual shareholder meeting for June 11, 2026, to be held online.Shareholders will vote on election of three Class III directors to serve until 2029.Meeting agenda includes advisory vote on compensation for named executive officers for fiscal 2025.Proposal also seeks ratification of BDO USA as independent registered accounting firm for fiscal 2026.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Whitehawk Therapeutics Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on April 28, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260428:nNDL5ZyZYL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","WHWK"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629305544","title":"Whitehawk Therapeutics' Antibody Drug Conjugates Indicate Potential Efficacy Against Cancer, Oppenheimer Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2629305544","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629305544?lang=en_us&edition=fundamental","pubTime":"2026-04-21 23:56","pubTimestamp":1776787016,"startTime":"0","endTime":"0","summary":"Whitehawk Therapeutics (WHWK) presented \"solid\" preclinical datasets for its early stage antibody drug conjugates, or ADCs, indicating \"substantial clinical evidence\" of their potential efficacy again","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["WHWK","BK4139","LENZ","BK4127","BK4539","OPY","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629039602","title":"Oppenheimer Sticks to Their Buy Rating for Whitehawk Therapeutics (WHWK)","url":"https://stock-news.laohu8.com/highlight/detail?id=2629039602","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629039602?lang=en_us&edition=fundamental","pubTime":"2026-04-21 20:17","pubTimestamp":1776773865,"startTime":"0","endTime":"0","summary":"In a report released today, Jeff Jones from Oppenheimer reiterated a Buy rating on Whitehawk Therapeutics, with a price target of $6.00. According ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/oppenheimer-sticks-to-their-buy-rating-for-whitehawk-therapeutics-whwk-blurbs-news-2?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/oppenheimer-sticks-to-their-buy-rating-for-whitehawk-therapeutics-whwk-blurbs-news-2?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["WHWK","OPY"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2629603809","title":"Analysts’ Opinions Are Mixed on These Healthcare Stocks: Whitehawk Therapeutics (WHWK), COMPASS Pathways (CMPS) and Monopar Therapeutics Inc (MNPR)","url":"https://stock-news.laohu8.com/highlight/detail?id=2629603809","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2629603809?lang=en_us&edition=fundamental","pubTime":"2026-04-21 19:00","pubTimestamp":1776769222,"startTime":"0","endTime":"0","summary":"Analysts have been eager to weigh in on the Healthcare sector with new ratings on Whitehawk Therapeutics (WHWK), COMPASS Pathways (CMPS) and Monopa...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-whitehawk-therapeutics-whwk-compass-pathways-cmps-and-monopar-therapeutics-inc-mnpr-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-opinions-are-mixed-on-these-healthcare-stocks-whitehawk-therapeutics-whwk-compass-pathways-cmps-and-monopar-therapeutics-inc-mnpr-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["CMPS","XLV","BK4139","MNPR","WHWK","BK4137","BK4585","BK4581","BK4588","HCSG","LABU","LU0128526141.USD","XBI","LU0029874061.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2628156937","title":"Whitehawk Therapeutics publishes HWK-016 preclinical presentation on MUC16-targeting ADC","url":"https://stock-news.laohu8.com/highlight/detail?id=2628156937","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2628156937?lang=en_us&edition=fundamental","pubTime":"2026-04-20 11:45","pubTimestamp":1776656716,"startTime":"0","endTime":"0","summary":"Whitehawk Therapeutics published preclinical data for HWK-016, a MUC16-targeting antibody-drug conjugate designed to bind non-shed MUC16 extracellular domain rather than circulating CA125.In cell assays, exogenous CA125 at 10,623 U/mL shifted HWK-016 antibody binding EC50 3-fold to 0.67 nM from 0.22 nM.In an ovarian cancer OVCAR-3 xenograft model, HWK-016 produced 108% tumor growth inhibition at 6 mg/kg with 4 complete responses out of 7 animals.Repeat-dose toxicology in cynomolgus monkeys showed highest non-severely toxic dose of 60 mg/kg with no mortalities reported.Whitehawk said HWK-016 is being evaluated in a Phase 1 study in advanced ovarian or endometrial cancers .Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. 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