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Ionis Pharmaceuticals

43.54

-0.4600-1.05%

Post-market: 43.610.0700+0.16%19:56 EDT

Volume:2.31M

Turnover:100.67M

Market Cap:7.24B

PE:-12.51

High:44.17

Open:44.17

Low:43.24

Close:44.00

52wk High:86.74

52wk Low:43.01

Shares:166.18M

Float Shares:161.92M

Volume Ratio:0.63

T/O Rate:1.43%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.4800

EPS(LYR):-2.3812

ROE:-105.50%

ROA:-12.42%

PB:16.45

PE(LYR):-18.28

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Overview Company News Filings

Ionis Pharmaceuticals, - Ulefnersen Demonstrates Favorable Safety and Tolerability Profile

THOMSON REUTERS

Ionis Pharmaceuticals, - Ulefnersen Demonstrates Statistically Significant Improvement on Primary Endpoint in Fus-ALS

THOMSON REUTERS

Ionis Announces Positive Topline Results from Phase 3 Fusion Study of Ulefnersen Marking Significant Milestone in Advancing First Potential Disease Modifying Treatment for Fus-ALS

THOMSON REUTERS

US Research Roundup-Boeing, Twilio, WP Carey

Ionis Pharmaceuticals, Inc. : JP Morgan Cuts Target Price to $70 from $76

THOMSON REUTERS

Cathie Wood’s ARK Investment buys 100K shares of Ionis Pharmaceuticals today

Movement Alert｜Ionis Pharmaceuticals Falls 5.01% in Regular Trading, Cardiovascular Pipeline Setbacks and Analyst Target Cuts Weigh on Shares

Movement Alert｜Ionis Pharmaceuticals Rises 5.03% in Regular Trading, Trading at $45.87

Movement Alert｜Ionis Pharmaceuticals Falls 5.25% in Regular Trading, Consecutive Cardiovascular Pipeline Failures Continue to Weigh on Shares

Movement Alert｜Ionis Pharmaceuticals Falls 6.29% in Regular Trading, Continued Pressure from Consecutive Heart Disease Drug Trial Failures

Ionis Pharmaceuticals Price Target Cut to $80.00/Share from $89.00 by Guggenheim

Ionis Pharmaceuticals price target lowered to $80 from $89 at Guggenheim

Guggenheim Reaffirms Their Buy Rating on Ionis Pharmaceuticals (IONS)

BofA Adjusts Price Target on Ionis Pharmaceuticals to $91 From $93

MT Newswires Live

Bank of America Securities Keeps Their Buy Rating on Ionis Pharmaceuticals (IONS)

U.S. Stocks on the MOVE-Best Buy, Peloton, Apple

Ionis Pharmaceuticals price target lowered to $84 from $87 at Raymond James

Royalty Pharma Falls After Novartis' Cholesterol Drug Fails in Study

U.S. Stocks on the MOVE-Sigma Lithium, Shake Shack, Novartis

Movement Alert｜Ionis Pharmaceuticals Falls 7.76% in Regular Trading, Partner Novartis Lp(a) Drug Fails Phase 3 Trial

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Pharmaceuticals...","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1117397601","title":"Movement Alert｜Ionis Pharmaceuticals Falls 5.25% in Regular Trading, Consecutive Cardiovascular Pipeline Failures Continue to Weigh on Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=1117397601","media":"Market Focus","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1117397601?lang=en_us&edition=fundamental","pubTime":"2026-09-17 03:13","pubTimestamp":1789586025,"startTime":"0","endTime":"0","summary":"On September 17, Ionis Pharmaceuticals fell 5.25% in regular trading, trading at $44.75/share, with turnover of $202 million, extending its recent downward trajectory.On the news front, the company's...","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"Ionis Slumps as TD Cowen Slashes Target After Pipeline Failures","news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1115680547","title":"Movement Alert｜Ionis Pharmaceuticals Falls 6.29% in Regular Trading, Continued Pressure from Consecutive Heart Disease Drug Trial Failures","url":"https://stock-news.laohu8.com/highlight/detail?id=1115680547","media":"Market 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The firm’s “quick ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-price-target-lowered-to-80-from-89-at-guggenheim-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/ionis-pharmaceuticals-price-target-lowered-to-80-from-89-at-guggenheim-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2667443246","title":"Guggenheim Reaffirms Their Buy Rating on Ionis Pharmaceuticals (IONS)","url":"https://stock-news.laohu8.com/highlight/detail?id=2667443246","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2667443246?lang=en_us&edition=fundamental","pubTime":"2026-09-15 19:35","pubTimestamp":1789472145,"startTime":"0","endTime":"0","summary":"Guggenheim analyst Debjit Chattopadhyay maintained a Buy rating on Ionis Pharmaceuticals yesterday and set a price target of $80.00. The company’s ...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/guggenheim-reaffirms-their-buy-rating-on-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/guggenheim-reaffirms-their-buy-rating-on-ionis-pharmaceuticals-ions-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2666235538","title":"BofA Adjusts Price Target on Ionis Pharmaceuticals to $91 From 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