Movement Alert|INSILICO Rises 5.07% in Regular Trading, Phase III First Dosing Milestone and Chairman Share Purchase Boost Sentiment

Market Focus
Sep 17

On September 17, INSILICO rose 5.07% in regular trading, trading at HK$53.0 per share, with turnover of HK$159 million.

The rally was driven by a dual catalyst. The company's core AI-driven candidate Rentosertib completed first patient dosing in its Phase III clinical trial GENESIS-IPF-3 at Peking Union Medical College Hospital on September 10. The 52-week study plans to enroll 320 idiopathic pulmonary fibrosis patients and marks a global milestone as the first generative AI-discovered drug to enter Phase III. Rentosertib is a potentially first-in-class TNIK-targeting small molecule inhibitor discovered via the company's proprietary Pharma.AI platform.

Additionally, Chairman and CEO Aleksandrs Zavoronkovs purchased 113,500 shares on the open market between September 4 and 7 using personal funds, raising his stake to approximately 8.02% of outstanding shares, as part of a broader plan to invest up to HK$16 million. Citi maintained a Buy rating with a target price of HK$85, designating the stock as its top pick in the AI drug discovery subsector.

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