On September 24, Viking Therapeutics fell 8.3% in after-hours trading, trading at $38.49/share, with turnover of approximately $9.89 million. The pullback followed two consecutive sessions of sharp gains driven by positive clinical data for its obesity drug candidate VK2735.
The sell-off reflects profit-taking pressure after the stock surged over 34% on September 22 and extended gains intraday on September 24, reaching $43.07. The rally was triggered by the company's announcement that its GLP-1/GIP dual agonist VK2735 demonstrated superior weight maintenance under reduced dosing frequency. Specifically, patients switching from weekly to biweekly injections preserved up to 97% of initial weight loss, while those on monthly dosing retained approximately 90%. Placebo comparators retained only about 61%. At the weekly 17.5mg dose, placebo-adjusted weight loss reached 22% at week 33.
While the clinical data validated VK2735's competitive positioning in the expanding obesity therapeutics market, the magnitude of the preceding rally created conditions for near-term consolidation. The company plans to explore oral dosing regimens in the next phase of the study.
Viking Therapeutics is a clinical-stage biopharmaceutical company focused on developing novel therapies for metabolic and endocrine disorders, with VK2735 as its lead obesity candidate in both injectable and oral formulations.
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